Introduction: Herbs play a vital role in our lives, particularly in the realm of medicine. Traditional medicine, in fact, relies heavily on medicinal plants, with approximately 3.3 billion people in developing countries using them regularly (Davidson, 2010).
Materials and Methods: Collection of Plant material, In-vivo Experimental Design/Animal Grouping of Testosterone Propionate Induction and Treatment using Aframomum meleguata.
Results: The damage to the prostate region were reversed on treatment with EAM. However, posterior karyolysis was observed in the hippocampus of rats treated with (2900 mg/kg) EAM alone.
Conclusion: The result obtained in the present study revealed that Aframomum meluegata leaf extract ameliorated testosterone-propionate–induced benign prostatic hyperplasia through its antioxidative, anti-inflammatory and anti-apoptotic effect.
Keywords: Benign prostatic hyperplasia (BPH), Center for Research and Development (CERAD), Aframomum meluegata
