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Comparative assessment of serum level of selenium and iron in 1st trimester of pregnancy with non-pregnant women

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Original Article

Author Details : Shreyans Prasad D Nilakhe, DVSS Ramavataram, Dilip M Kava*, Jyoti Patel

Volume : 6, Issue : 4, Year : 2019

Article Page : 452-457

https://doi.org/10.18231/j.ijcbr.2019.095

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Abstract

Introduction: Pregnancy is dynamic anabolic state in women’s life. During pregnancy women undergo
profound hormonal, metabolic and physical changes.
Aim of the present study was to compare the serum level of selenium and iron between pregnant and
non-pregnant women.
Materials and Methods: The present study was carried out in 50 first trimester pregnant women and 50
non pregnant women at tertiary care hospital in Surat, in age group of <25>30
years and in BMI groups of <23> Blood was collected and serum was analyzed for selenium and iron concentration in atomic absorption
spectrophotometry (AAS).We have also measured anthropological parameter like height, weight and based
on this BMI calculated. SPSS software used for statistical analysis.
Result: There was a significant lower level of serum selenium (p<0> found in 1st trimester pregnant women compared to non-pregnant women. There was a significant
decreased in selenium level in all BMI group in pregnant women except in 30 kg/m2 group and there was
a decreased in serum iron level in all BMI group in pregnant women compared to non-pregnant women.
Conclusion: There was a significant decrease in serum selenium and iron level in 1st trimester of pregnant
women com pared to non- pregnant women, which indicate that during pregnancy requirement of trace
elements increase to meet demand for fetus growth. A reduction in maternal selenium concentration during
pregnancy can lead to various disorders such as miscarriage, premature birth, preeclampsia, pregnancy
include hypertension, low birth weight, retinopathy of prematurity etc.

Keywords: Selenium, Iron, Atomic absorption spectrophotometry.

How to cite : Nilakhe S P D, Ramavataram D, Kava D M, Patel J, Comparative assessment of serum level of selenium and iron in 1st trimester of pregnancy with non-pregnant women. Int J Clin Biochem Res 2019;6(4):452-457

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