International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 6, Issue : 4, Year : 2019
Article Page : 601-605
https://doi.org/10.18231/j.ijcbr.2019.124
Abstract
Ovarian cancer is the most common and most lethal gynecologic malignancy. It is one of the most leading
cancers in Indian women. The urge for the early detection of ovarian cancer continues to be one of the most
important issues in women’s health care. The cause for ovarian cancer may be due to increased oxidative
stress, heredity, dietary deficiency etc. As zinc is essential for cytotoxic/tumor suppressor effect and it plays
very important role in cancer progression. In ovarian cancer the level of zinc in blood is usually decreased.
So, the hypothesis of the study is to know the association between the serum zinc levels and the ovarian
cancer marker, CA125. Aim of the study is to correlate the serum Zinc levels with serum CA 125 in healthy
controls and ovarian cancer subjects.
Totally 90 subjects are enrolled in the study. Out of this 74 were controls and 16 were ovarian cancer
subjects. The serum CA 125 was increased in ovarian cancer patients compared to controls. Whereas,
serum Zinc was decreased in ovarian cancer patients compared to controls. As well as there was indeed a
strong association of serum Zinc and CA 125 in ovarian cancer patients.
Hence measurement of serum Zinc, an inexpensive assay could be used as an auxiliary marker along with
CA 125 in screening of ovarian cancer.
Keywords: Zinc, Ovarian cancer, Marker CA 125, Serum CA 125.
How to cite : Maradi R, Khader N A, Kishan K, Zinc as an auxiliary marker along with Cancer Antigen 125 in ovarian cancer. Int J Clin Biochem Res 2019;6(4):601-605
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