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Profile of cord blood lipids in term newborns in parakou (Benin)

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Original Article

Author Details : Moutawakilou Gomina*, Achille Obossou, Gloria Amevor, Tarik Salifou, Simon Akpona

Volume : 7, Issue : 1, Year : 2020

Article Page : 111-115

https://doi.org/10.18231/j.ijcbr.2020.022

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Abstract

Introduction: Lipid profile abnormalities at birth indicate that initial genetic inheritance is already at risk
of developing a cardiovascular disease.
Objective: Investigate the profile of umbilical cord blood lipids of term newborns in Parakou (Benin).
Materials and Methods: This research work was a cross-sectional study with descriptive and analytical
purpose, based on prospective collection of data. It involved term newborns recruited through complete
census in three health-care facilities located in the city of Parakou (Republic of Benin), after the informed
consent read and approved by their respective mothers and ethics advice. The study data were collected
from March 1 to May 30, 2017 by measurements of anthropometric and lipid parameters from umbilical
cord blood using endpoint enzymatic methods. LDL cholesterol was obtained by Friedewald formula.
Results: A total of 120 newborns were recruited (60 males and 60 females). Their mean weight was
estimated at 2992.68 355.08 g with extremes from 2120 to 3125 g. The mean values of lipid parameters
were: total cholesterol (0.68 0.25 g/L), HDL cholesterol (0.29 0.12 g/L), LDL cholesterol (0.31 0.16
g/L) and triglyceride (0.39 0.27 g/L). There was no significant difference in mean values of newborns
’ lipid parameters between both sexes (p > 0.05). Total cholesterol and HDL cholesterol were normal,
respectively in 75.83% and 85% of cases; hypotriglyceridemia was observed in 61.67% of newborns.

Keywords: Newborn, Lipids, Hypotriglyceridemia, Umbilical cord, Benin.

How to cite : Gomina M, Obossou A, Amevor G, Salifou T, Akpona S, Profile of cord blood lipids in term newborns in parakou (Benin). Int J Clin Biochem Res 2020;7(1):111-115

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