International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Null
Author Details :
Volume : 2, Issue : 4, Year : 2015
Article Page : 233-235
Abstract
Background: The alterations (increase or decrease) of intracellular and extracellular enzymes or components in developing phase of disease are called markers. Variations in biochemical markers like Cardiac Troponins-I (cTnI), Creatine kinase (CK) and its isoform Creatine kinase-MB (CK-MB) may correlate with the extent of myocardial damage in Acute Myocardial Infarction (AMI). Association of serum electrolytes and urea levels were undertaken in this study as adjunctive parameters along with cardiac markers, which probably helps in better prognosis of AMI.
Materials and Methods: 120 subjects were included in this study and divided equally as study and control groups. Estimation of cTnI, CK, CK-MB, Serum sodium, potassium, chloride and urea were done in all the participants. Data were compared by using student `t’ test and chi-square test (SPSS version 17.0).
Results: There were statistically significant decreased levels of serum sodium (p<0.001), potassium (p<0.001) and elevated levels of urea (p<0.001) observed in AMI. But, the levels of serum chloride didn’t show any significant correlation between case and control groups.
Conclusion: The present study was conducted to make an effort to find out association of abnormal levels of electrolytes and urea in AMI. Further studies are required to know the role of these correlations in prognosis of clinical condition.
How to cite : Mudaraddi R, Kulkarni S P, Trivedi D J, Patil V S, Pr, Association of Serum Electrolytes and Urea Levels with Cardiac Markers in Acute Myocardial Infarction. Int J Clin Biochem Res 2015;2(4):233-235
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