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Prevalence of thyroid dysfunction in metabolic syndrome - A cross-sectional study

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Original Article

Author Details : Shravya R Ginnaram, D Sridevi*, Amrut Arvindrao Dambal, Sushritha Y Reddy, Abhinav R Pingle

Volume : 7, Issue : 3, Year : 2020

Article Page : 374-379

https://doi.org/10.18231/j.ijcbr.2020.080

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Abstract

Background and Objectives: Literature review have hypothesized that the rising incidence of metabolic
syndrome worldwide has been associated with an increased risk of thyroid disorders. The aim & objective
of our study was to diagnose patients with metabolic syndrome based on IDF criteria, to estimate T3, T4,
TSH levels among these patients and to observe the correlation between thyroid dysfunction and metabolic
syndrome.
Materials and Methods: Our study was a hospital based age and sex matched cross-sectional study with
a total of 120 participants (60 cases and 60 controls) between 30 - 50 years old conducted at Malla Reddy
Institute of Medical Sciences, Hyderabad, India. Ethics approval was obtained from the Institutional Ethics
Committee.
Results: Our study found that both men and women with metabolic syndrome had a higher percentage of
thyroid disorders compared to the controls without metabolic syndrome. Among the cases, women were
found to present with more thyroid abnormalities than men.
Conclusion: Routine screening with thyroid function tests should be implemented for all patients with
metabolic syndrome, especially females. The coexistence of these two entities can increase the risk for
cardiovascular disease. Early detection and intervention can help reduce the progression of CVD.

Keywords: Metabolic Syndrome(MetS), Cardiovascular Disease(CVD), Type 2 Diabetes Mellitus (T2DM), Subclinical Hypothyroidism (SCH), Thyroid Stimulating Hormone (TSH), Thyroxine (T4), Triiodothyronine(T3).

How to cite : Ginnaram S R , Sridevi D, Dambal A A , Reddy S Y, Pingle A R, Prevalence of thyroid dysfunction in metabolic syndrome - A cross-sectional study. Int J Clin Biochem Res 2020;7(3):374-379

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