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Correlation of glycated haemoglobin with fasting and post prandial blood glucose in Type 2 diabetes

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Original Article

Author Details : K Vani*, A Renuka

Volume : 7, Issue : 3, Year : 2020

Article Page : 380-383

https://doi.org/10.18231/j.ijcbr.2020.081

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Abstract

Background: Diabetes mellitus is a group of metabolic disorders characterized by high blood sugar levels
and this chronic hyperglycemia is responsible for most of the complications of the disease. Glycated
haemoglobin or HbA1C is a marker of this hyperglycemia and its complications. The aim of this study
is to find out the correlation between HbA1C and FBS, PPBS and hence its effectiveness in assessing the
glycemic contol in type 2 diabetic patients.
Materials and Methods: In this cross sectional study, FBS, PPBS and HbA1C values were recorded in
the study population which includes 605 type 2 diabetic patients visiting the hospital. FBS and PPBS were
estimated using GOD- POD method. HbA1C was analyzed using particle enhanced immunoturbidimetric
method and the data analysed and correlated with FBS and PPBS.
Results: There was a significant correlation between FBS, PPBS and HbA1C in the study population. It
has also been found that PPBS shows a marginally better correlation(0.79) with HbA1C than FBS(0.77).
This emphasizes the role of HbA1C as an indicator of blood glucose control, as it correlates well with FBS
and PPBS.
Conclusion: Maintenance of strict glycemic control retards the development of complications of diabetes,
which improves the quality of life of a diabetic patient. This glycemic control can be assessed with
reasonable accuracy using HbA1C, as it has been found to correlate well with FBS and PPBS levels, more
so with the PPBS levels.

Keywords: Diabetes mellitus, FBS(Fasting Blood Sugar), HbA1c, Hyperglycemia, PPBS (Post Prandial Blood Sugar).

How to cite : Vani K , Renuka A , Correlation of glycated haemoglobin with fasting and post prandial blood glucose in Type 2 diabetes. Int J Clin Biochem Res 2020;7(3):380-383

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