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Cognizance of stem cells: A gist

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Review Article

Author Details : Debalina Sen, Venkata Bharat Kumar Pinnelli, Wilma Delphine Silvia C R*, Priyanka A

Volume : 8, Issue : 1, Year : 2021

Article Page : 1-8

https://doi.org/10.18231/j.ijcbr.2021.001

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Abstract

Stem cells are undifferentiated cells which usually arises from one cell (clonal) and has the characteristic of self renewal i.e ability to proliferate and differentiate into various styles of cells (potent). Depending upon the potencies there are different sources of stem cells. Pluripotent cells has the flexibility to differentiate into tissues from the three germ layers. There are various sources of stem cells with varying potencies. Pluripotent cells have the ability to differentiate into tissue from all 3 germ layers (endoderm, mesoderm,
and ectoderm). Multipotent stem cells may differentiate into tissue derived from a single germ layer like mesenchymal stem cells which form adipose tissue, bone, and cartilage thanks to the limited generation of most somatic cells, stem cells’ capacity to replenish damaged somatic cells and maintain a self-renewing reservoir of progenitors is crucial for homeostasis in many tissues of the many organisms. Thus, there’s an immense interest in understanding the mechanisms for self-renewal and differentiation in stem cells, given their potential applications in regenerative medicine and studies of human development or aging during this article we’ll describe about stem cells and various varieties of stem cells.

Keywords: Stem cells, Differentiation, Adult stem cells, Embryonic stem cells, Induced pluripotent stem cells.

How to cite : Sen D , Pinnelli V B K, Wilma Delphine Silvia C R, Priyanka A, Cognizance of stem cells: A gist. Int J Clin Biochem Res 2021;8(1):1-8

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