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Cardiometabolic profile of type 2 diabetic subjects in Libreville

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Original Article

Author Details : Aude Syntia MBANG BENGONE*, Rosalie NIKIEMA-NDONG, Daniella NSAME, Edwige NNEGUE EDZO, Kissy NZOUGHE, Clément OBAME ENGONGHA, Félix OVONO ABESSOLO

Volume : 8, Issue : 1, Year : 2021

Article Page : 15-21

https://doi.org/10.18231/j.ijcbr.2021.004

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Abstract

Type 2 diabetes is the chronic metabolic disease associated with cardiovascular, renal and neurological complications, responsible for morbidity and mortality. In addition, the incidence of cardiovascular disease was 10.3 out of 1000 type 2 diabetics per year in low-income countries like Gabon. Thus, this work was setup to determine the cardiometabolic profile of type 2 diabetic subjects in Libreville.
Materials and Methods: This was a cross-sectional analytical study, which took place at the Endocrinology Department of the University Hospital Center of Libreville (CHUL) and at the Biochemistry Laboratory of Health Sciences University (USS). 210 subjects were enrolled, including 95 diabetics and 115 controls. Their anthropometric values were recorded and biochemical parameters obtained by spectrophotometric methods. Metabolic syndrome was defined according to NCEP ATP III criteria, and 10-years cardiovascular risk was assessed using Framingham and American Heart Association (AHA) / ACC risk scores.
Results: The metabolic syndrome was found among 75.8% of diabetics against 24.2% among controls (p = 0.000). In all, 42.1% of diabetics
had a high cardiovascular risk by the Framingham equation versus 6.1% for the controls and 41.1% with the AHA / ACC score versus 4.3% for the controls. Diabetic women were more affected than men (54.6% against 13.8% p = 0.000).
Conclusion: Type 2 diabetics should undergo intensive management of cardiovascular risk factors in order to reduce the level of cardiovascular risk. Thus their life shall be improved by reducing morbidity and mortality.

Keywords: Type 2 diabetes, Cardiovascular risk factors, Metabolic syndrome, Cardiometabolic, Framingham.

How to cite : Bengone A S M, Nikiema-ndong R , Nsame D , Edzo E N, Nzoughe K , Engongha C O , Abessolo F O , Cardiometabolic profile of type 2 diabetic subjects in Libreville. Int J Clin Biochem Res 2021;8(1):15-21

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