International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Null
Author Details :
Volume : 3, Issue : , Year : 2016
Article Page : 72-75
Abstract
Background & objectives: Neutrophil Gelatinase Associated Lipocalin NGAL predicts Acute Kidney Injury earlier than creatinine in cardiac surgery patients. This study aims at understanding the correlation between the two biomarkers.
Methods: 53 patients who underwent major cardiac surgery were included in the study. Venous blood samples were collected before surgery and at 4 hours after surgery to estimate plasma NGAL and before surgery, at 4 hours, 24 hours, 48 hours and 72 hours after surgery from the patients to estimate serum creatinine. Correlation analysis was done between NGAL and creatinine using Pearson Correlation Coefficient.
Results: The correlation coefficients for plasma NGAL values at 4 hours after surgery with the serum creatinine values were r = 0.87 at 4 hours, r = 0.86 at 24 hours, r = 0.91 at 48 hours and r = 0.87 at 72 hours after surgery.
Interpretation: The correlation coefficient values shows that plasma NGAL values at 4 hours after surgery were highly correlated with the serum creatinine values at 4 hours, 24 hours, 48 hours and 72 hours after surgery.
Conclusion: This study shows that NGAL values are highly correlated with creatinine values.
Keywords: NGAL, Creatinine, Aki, Cardiac Surgery
How to cite : Anusha.r, Madhubala.v, A Correlation Study between Plasma Neutrophil Gelatinase Associated Lipocalin and Serum Creatinine in Cardiac Surgery Patients. Int J Clin Biochem Res 2016;3():72-75
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