Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 10, Issue : 2, Year : 2023
Article Page : 134-139
https://doi.org/10.18231/j.ijcbr.2023.022
Abstract
The study investigated the effect of Terminalia arjuna bark powder on circulatory immune complexes and total immunoglobulins level in Kosali breed of cattle environmentally exposed to arsenic contamination through water and fodder. Arsenic concentration was significantly (p<0.05) higher in drinking water, fodder and cattle blood samples collected from the arsenic contaminated area as compared to uncontaminated area (control area). Kosali cattle reared in the arsenic contaminated area showed significantly (p<0.05) elevated circulatory immune complexes with decreased level of plasma total immunoglobulins compared to the control area. Terminalia arjuna bark powder was administered orally @ 40 mg/kg. b. w. daily for 30 days to eight Kosali cattle (treatment group) selected from the arsenic contaminated area. Eight Kosali cattle each from arsenic contaminated and uncontaminated area (without any treatment) served as exposure control and healthy control respectively. Kosali cattle of the treatment group exhibited significant (p<0.05) decrease in the level of circulatory immune complexes; and increase in the total immunoglobulin concentration to the level comparable to that of healthy control.
Keywords: Arsenic, Immune complexes, Terminalia arjuna, Immunoglobulin.
How to cite : Dash S K, Immune complexes in Kosali breed of cattle naturally exposed to arsenic contamination: Attenuation by Terminalia arjuna. Int J Clin Biochem Res 2023;10(2):134-139
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