International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 10, Issue : 3, Year : 2023
Article Page : 228-231
https://doi.org/10.18231/j.ijcbr.2023.040
Abstract
Aim & Background: The present study was conducted toexamine the Hepatoprotective activity against the carbon tetrachloride toxicity in Wister rats.
Materials and Methods: The Petroleum ether, ethyl acetate and methanol extract of Ageratum canyzoides was prepared and evaluated for phytochemical screening. The serum level of glutamic oxaloacetate transaminase (SGOT) Glutomicpyruvate transaminase (SGPT) and bilirubin were investigated for the assessment of hepatoprotective activity of ethyl acetate of extract Ageratum conyzoides.
Results: Additionally, the histological changes in liver were studied. The primary phytochemical investigation of the extract of Ageratumcanyzoides revealed the presence of Flavonoids, tannins, and carbohydrates. Pretreatment with ethyl acetate extract of Ageratumconyzioide showed a significant (P<0>
Conclusion: The outcomes of histology study revealed that there was significant reversal of histological functions of liver. In conclusion, the findings of study validated that the Ageratum canyzoides can improve CCl–induced hepatic toxicity.
Keywords: Hepatoprotective, Antioxidants, Histopathpology, Carbon tetrachloride, Hepatotoxicity
How to cite : Sharma M, Soni M, Gupta A, Protective effect of Ageratum conyzoides against carbon tetrachloride –induced hepatic damage in rats. Int J Clin Biochem Res 2023;10(3):228-231
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