International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Short Communication
Author Details :
Volume : 10, Issue : 3, Year : 2023
Article Page : 251-254
https://doi.org/10.18231/j.ijcbr.2023.044
Abstract
Leukocyte platelet-rich fibrin (L-PRF) is an autologous biomaterial used in regenerative medicine and tissue healing. This review emphasizes the role of growth factors and cytokines in L-PRF, which contribute significantly to the healing process in various clinical scenarios. The analysis focuses on the controlled release of Platelet-derived growth factors (PDGF), Fibroblast growth factors (FGF), and Vascular endothelial growth factors (VEGF), demonstrating a propensity to promote angiogenesis and stimulate the migration and proliferation of cells necessary for tissue regeneration. The review also examines the roles of anti-inflammatory and pro-inflammatory cytokines, including Interleukins (IL-1, IL-4, IL-10, IL-6) and Tumor necrosis factor-alpha (TNF-?), and Interferon-gamma (IFN-?), in modulating the inflammatory response during tissue healing. The goal of this comprehensive review is to enhance the understanding of L-PRF and its constituent factors, opening avenues for harnessing its potential in regenerative medicine. The bioactive components within L-PRF stimulate tissue healing and repair, creating an optimal environment for tissue regeneration.
Keywords:Cytokines, L- PRF, Growth factors, Platelet rich fibrin.
How to cite : Lowenstein A, Patel M, Mourão C F, Harvesting the biochemical potential of L-PRF with their growth factors and cytokines. Int J Clin Biochem Res 2023;10(3):251-254
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