International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 3, Issue : 2, Year : 2016
Article Page : 134-138
Abstract
Background: Type 2 diabetes mellitus is a worldwide endemic disease. Dyslipidemia is also a frequent disorder associated with diabetic patients. The present study is an attempt to link that elevated levels of adenosine deaminase in Type 2 diabetes mellitus patients augment hyperlipidemia.
Material and Methods: The subjects included in this study were divided into 3 groups. Group A consisted of 30 normal healthy individuals who served as controls with no history of DM. Group B consisted of 30 patients of Type 2 Diabetes Mellitus both males & females in the age group of 40-65 years on oral hypoglycaemic drugs with HbA1c <7%. Group C consisted of 30 patients of Type 2 Diabetes Mellitus both males & females in the age group of 40-65 years on oral hypoglycaemic drugs with HbA1c >7 %. Serum levels of fasting blood sugar, HbA1c, ADA and lipid profile were estimated in all the subjects under study.
Results: All the three parameters, FBS, HbA1c and ADA levels were found to be increased in the patients of Type 2 DM as compared to controls. The mean S. Triglyceride and S. VLDL-C levels were significantly elevated in group C as compared to Group A. The mean serum levels of S. HDL-C showed a decreasing trend with increase in levels of HbA1c.
Conclusion: From the present study, it was concluded that dyslipidemia was found to be higher in diabetic patients with respect to healthy controls. The lipid abnormality (dyslipidemia) associated with type 2 diabetes typically consists of elevated triglyceride and decreased HDL-C levels.
Keywords: Diabetes Mellitus type 2, Adenosine deaminase (ADA), Glycated haemoglobin (HbA1c), Fasting blood Sugar (FBS)
How to cite : Kaur A, Kukeraja S, Singh T, Sandhu I S, Singh G, Effect of adenosine deaminase activity on lipid profile in patients of type 2 diabetes mellitus. Int J Clin Biochem Res 2016;3(2):134-138
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