International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
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Original Article
Author Details :
Volume : 11, Issue : 1, Year : 2024
Article Page : 32-38
https://doi.org/10.18231/j.ijcbr.2024.006
Abstract
Background of Study: Any compound or combination of substances meant to prevent, eradicate, repel, or mitigate any pest is known as a pesticide. Despite the benefits of using pesticides for pests, weeds, and disease control, there have been concerns about adverse effects of these compounds on the human health. This cross-sectional study was designed to assess the cardiac function of farmers occupationally exposed to pesticides, in Gboko Local Government Area, Benue State, Nigeria.
Materials and Methods: One hundred ten (110) participants comprising 70 farmers and 40 controls were recruited for the study using a multi-stage random sampling technique. They were aged between 20-60 years and were age-matched. Five (5) ml of fasting blood samples were collected from each participant for the determination of Apolipoprotein A1 (ApoA1), Apolipoprotein B-100 (ApoB100) and Troponin I level using standard laboratory methods. Also, the body mass index (BMI), systolic blood pressure (SBP) and diastolic blood pressure (DBP) of the participants were also determined.
Results: The results showed significantly lower mean BMI (23.02±3.94 Vs 24.94±3.12; p= 0.031) and serum ApoA1 (150.73±13.52 Vs 167.27±15.65; p=0.024) while the mean SBP (140.49±19.34 Vs 119.75±10.30; p=0.000), DBP (82.86±12.16 Vs 77.53±7.76; p=0.014) and mean serum Troponin-I (3.11±5.46 Vs 1.38±0.15; p=0.049) levels were significantly higher in the farmers compared to control respectively. However, there was no significant difference in the mean serum ApoB-100 level in the farmers when compared to the control group (p=0.104).
Conclusion : This study showed that the farmers had lower body mass index and higher serum levels of apoA-I, apoB-100, and Troponin I, as well as systolic and diastolic blood pressure, as compared to the control group. Nonetheless, in both the test and control groups, these results fell within the typical reference ranges. Further longitudinal research is required to gain a deeper understanding of the effects of pesticide exposure on cardiac function in farmers.
Keywords: Pesticides exposure, Cardiac function, Apolipoprotein, Troponin-I, Body mass index
How to cite : Obiorah O M, Meludu C S, Onah E C, Okeke C S, Ogbodo C E, Akaeme C J, Agwaraonye K C, Assessment of cardiac function in farmers occupationally exposed to pesticides in gboko local government area, benue state. Int J Clin Biochem Res 2024;11(1):32-38
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