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Will controlled monitoring of biochemical profile help in better prognosis of diabetic foot ulcer?

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Case Report

Author Details : Drishya P Nair*, Asha Khubchandani, Anil Kumar A S

Volume : 11, Issue : 4, Year : 2024

Article Page : 269-272

https://doi.org/10.18231/j.ijcbr.2024.040

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Abstract

Diabetes Mellitus affects more than 400 million people worldwide and that number is growing rapidly. India is the country with largest number of diabetic patients in the world. Diabetic foot ulcer is one of the common causes of hospital admissions among diabetics in India.This study was aimed at creating a database on biochemical profile of diabetic foot ulcer patients and to see if they can be used to detect and prevent progressing complications and also to monitor treatment progress. A cross sectional study was conducted amongst 50 diabetic foot ulcer patients, biochemical parameters such as HbA1c, S. urea, S. creatinine, S. electrolytes, S. protein, S. albumin, S. SGPT, S. acetone, S. cholesterol, S. triglycerides and S. HDL were estimated from the time of hospital admission and in successive follow up. The population study group age was between 40 to 65 years with 60 percent being males. Among 50 patients there was a relative and gradual increase in values of HbA1c, Creatinine, Cholesterol and Triglycerides. whereas there is a decrease in values observed in parameters like Protein, Albumin and Sodium. Novel diagnostics are able to rapidly detect some of the most dangerous consequences of diabetic foot ulcer and can help to guide therapy. Therefore, preventive and evidence -based guidelines should be followed for diabetic wound management.
Take home message: Diabetic foot ulceration is a major health problem along with wound healing. Its management must also focus on identifying and correction of these biochemical changes and other contributing factors.

Keywords: Diabetic foot ulcer, HbA1c, Biochemical profile

How to cite : Nair D P, Khubchandani A, Anil Kumar A S, Will controlled monitoring of biochemical profile help in better prognosis of diabetic foot ulcer?. Int J Clin Biochem Res 2024;11(4):269-272

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