International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 4, Issue : 2, Year : 2017
Article Page : 126-128
Abstract
Introduction: Thyroid dysfunctions are known to influence lipid metabolism significantly, affects lipoprotein metabolism. Hyperthyroidism is associated with lipid alterations mainly concerning total and LDL cholesterol.
Materials and Method: It was a case control study. The cases and controls were screened for serum thyroid profile and complete lipid profile, the values were compared with that of normal healthy subjects. The cases were divided into two groups after studying the thyroid profile i.e. subclinical hyperthyroidism (characterized by low serum TSH with normal T4) and overt hyperthyroidism (characterized by low TSH and with elevated FT4).
Results: The descriptive data was given as mean ± standard deviation. The statistical analysis was done by ANOVA and student t test. The mean difference was significant at the 0.05 level and statistically insignificant when the p value obtained was greater than 0.05. The mean serum total cholesterol & LDL levels were decreased in patients of overt hyperthyroidism as compared to controls and the difference between the levels was statistically insignificant. But the mean serum TG remain unchanged in patients and the difference was statistically insignificant. In the cases of subclinical hyperthyroidism the mean serum levels of total cholesterol, LDL & TG were decreased in patients as compared to controls & the difference was statistically insignificant. But the mean serum HDL levels was significantly decreased in patients as compared to controls.
Conclusion: Thyroid function test for screening of thyroid dysfunction is great importance in all dyslipidemic patients. It is also of cardinal importance in all patients with unexpected improvement or worsening of their lipid profile. So underlying thyroid disorders should be recognized and treated in patients with dyslipidemia especially when the results are unforeseen.
Keywords: Thyroid dysfunction, Hyperthyroidism, Lipid profile, Dyslipidemia
How to cite : Sharma A, Kaur J, Kaur A, Uppal N, Kaur M, Evaluation of serum lipid profile in patients with hyperthyroidism. Int J Clin Biochem Res 2017;4(2):126-128
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