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Comparison of the analytical techniques of hba1c estimation by immunoturbidimetric and HPLC methods in diabetic and pre- diabetics patients

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Original Article

Author Details : A .G. Thivyah Prabha

Volume : 4, Issue : 2, Year : 2017

Article Page : 187-190

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Abstract

Aims & Objectives: The aim of the study is to compare the available analytical methods of measurement of HbA1c like immunoturbidimetric and HPLC methods.
Materials and Method: Total of 150 pre-diabetic and diabetic patients are included in the study. HbA1c was measured by immunoturbidimetric and HPLC methods as these are the common methods used by the clinical laboratories.
Results: The HbA1c values of two methods have a significant difference. The value of immunoturbidimetric method was less than the HPLC method. The two methods correlated with the correlation coefficient of 0.972.
Conclusion: Both the methods are reliable and show a strong correlation .Even though the immunoturtbidimetric values are low it is specific and more cost effective than the HPLC methods. HPLC is a sensitive method.

Keywords: HbA1C, Immunoturbidimetric, HPLC, Diabetics, Prediabetics

How to cite : Prabha A . T, Comparison of the analytical techniques of hba1c estimation by immunoturbidimetric and HPLC methods in diabetic and pre- diabetics patients. Int J Clin Biochem Res 2017;4(2):187-190

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