International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 4, Issue : 3, Year : 2017
Article Page : 249-252
Abstract
Introduction: Despite impressive strides in diagnosis and management over the past three decades, acute myocardial infarction (AMI) continues to be a major public health problem in the industrialized world and is becoming an increasingly important problem in developing countries. Xanthine oxidase in ischemic conditions of the heart may play an important role in generating free radical mediated damage.
Aim of the Study: To measure the levels of xanthine oxidase activity in myocardial infarction patients.
Materials and Method: The study was conducted from the month of June 2011 to May 2012, at MGM Hospital, Warangal blood samples of 30 patients diagnosed as acute myocardial infarction were collected and subjected to plasma xanthine oxidase activity.
Results: 60% of AMI patients belonged to 51-60 years age group. There was significant increase in mean values in Xanthine oxidase activity levels in (p < 0.001) in the study group as compared to controls.
Conclusion: Xanthine oxidase is good markers in identifying AMI. They all can be used together as multiple markers to increase their efficiency as markers of AMI. The AST & LDH though exhibited good sensitivity, lack specificity. Hence they should not be used as individual markers.
Keywords: Acute myocardial infarction, Male patients, Xanthine oxidase, Mycocardial injury, Free radicals
How to cite : Gayatri S, Kathyaini R, Xanthine oxidase -oxidase stress marker in acute MI patient: a study at a teaching hospital in Telangana. Int J Clin Biochem Res 2017;4(3):249-252
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