International Journal of Clinical Biochemistry and Research

Print ISSN: 2394-6369

Online ISSN: 2394-6377

CODEN : IJCBK6

International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...

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Original Article


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338-341


Authors Details

S. Kesav, D. Ponnudhali


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Serum ferritin in pre-diabetes & diabetes mellitus type 2 and its relationship with glycemic status


Original Article

Author Details : S. Kesav, D. Ponnudhali

Volume : 4, Issue : 4, Year : 2017

Article Page : 338-341


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Abstract

Introduction: Emerging scientific evidence suggests an increased prevalence of elevated serum ferritin levels in diabetes mellitus type 2. Serum ferritin, being a reliable marker of body iron stores, have been related to glucose intolerance.
Aim and Objectives: To analyze the serum ferritin levels in individuals having pre-diabetes and diabetes and to study its association with fasting blood glucose levels.
Materials and Method: It is a cross-sectional study conducted in diabetic (n=40), pre-diabetic (n=40) and healthy individuals (n=40). Serum ferritin & fasting glucose levels were analyzed and compared among the groups. BMI was calculated and analyzed in all the groups.
Statistical analysis: Statistical analysis done using SPSS 23 software. Mean and standard deviations of the parameters were compared using one way Analysis of variance (ANOVA) and Pearson’s correlations done for serum ferritin, glucose and BMI.
Results: Serum ferritin was found to be significantly increased (p<0.000) in the diabetic (74.68 ± 22.74µg/l) compared to pre-diabetic (47.53± 14.46µg/l) and in pre-diabetic compared to healthy individuals (25.0 ± 1.71µg/l). Positive correlations were found among serum ferritin, fasting blood glucose and BMI.
Conclusion: Serum ferritin could have an influential role in glucose homeostasis and its elevation in pre-diabetes and diabetes could have important therapeutic and prognostic implications.

Keywords: Ferritin, Pre-diabetes, Oxidative stress, Fasting blood glucose, Diabetes mellitus type 2


How to cite : Kesav S, Ponnudhali D, Serum ferritin in pre-diabetes & diabetes mellitus type 2 and its relationship with glycemic status. Int J Clin Biochem Res 2017;4(4):338-341

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