Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 4, Issue : 4, Year : 2017
Article Page : 383-386
Abstract
Introduction: Preeclampsia is a hypertensive disorder of pregnancy characterized by endothelial dysfunction. The present study was planned to assess and compare the levels of serum Lipoprotein (a) and lipid profile in preeclampsia and normal pregnant women and to determine the association of Lp (a) with severity of the disease.
Materials and Method: The study comprised of 60 preeclamptic women and 30 normal pregnant women in third trimester of pregnancy. The serum levels of lipoprotein (a) [Lp (a)], triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL) and very low density lipoprotein (VLDL) were determined.
Results: A significant alteration in Lp (a) and lipid profile parameters was observed in preeclamptic patients. Serum Lp (a), TG and VLDL were significantly increased while HDL was significantly decreased in preeclamptic group compared to normal pregnant women. Positive correlation was found between serum Lp (a) and blood pressure in preeclampsia patients.
Conclusion: The present study demonstrates a dyslipidemic profile in preeclamptic patients. These findings are significant in understanding the pathologic processes of preeclampsia and may help in developing strategies for prevention and early diagnosis of the disorder.
Keywords: Pre-eclampsia, Dyslipidemia, Lipid profile, Lipoprotein (a)
How to cite : Aghade S M, Bavikar J S, Asegaonkar S B, Assessment of Lipoprotein (a) and Lipid Profile Pattern in patients of Pre-Eclampsia. Int J Clin Biochem Res 2017;4(4):383-386
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