International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 4, Issue : 4, Year : 2017
Article Page : 413-415
Abstract
Introduction: Vitamin D is an important component in regulating the biological functions of the body in various ways. Many studies repeatedly explained the role of vitamin D in the pathogenesis and treatment of various diseases. Recent studies proved a correlation between vitamin D deficiency and prevalence of Type 2 Diabetes and its complications.
Objective: to find out the possible correlation between Vitamin D and T2DM. Mainly in this study we have tried to correlate serum 25(OH) D levels with HbA1c levels.
Materials and Method: The present study was carried out in the Department of Biochemistry on 120 subjects patient in the age group of 35-70 years, attended OP in Hind Institute of Medical Sciences. Among them 60 healthy subjects enrolled as control group remaining 60 T2DM patients were served as case group. Serum 25hydroxyvitamin D levels were estimated by chemiluminescence immunoassay (CLIA), glycosylated hemoglobin (HbA1c) was measured by IFCC method by using ALERA AFINION AS 100.
Results: The concentration of serum 25-OH vitamin D levels were significantly (p<0.0001) lower in cases (22.92±6.66) as compared to the controls (35.96± 8.46). There was negative correlation found between 25-OH vitamin D levels and glycosylated hemoglobin (HbA1c) in cases of type 2 DM.
Conclusions: Prevalence of hypovitaminosis D was appeared to be more common T2DM patients in compare to non diabetic healthy population. There is a negative correlation exists between serum 25 hydroxy vitamin D and HbA1C (glycemic Control).
Keywords: Type 2 Diabetes Mellitus, HbA1C, Hypovitaminosis D
How to cite : Shaheen S, Chauhan H, Mishra N, Association between type 2 diabetes mellitus and hypovitaminosis D. Int J Clin Biochem Res 2017;4(4):413-415
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