Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 5, Issue : 2, Year : 2018
Article Page : 206-208
https://doi.org/10.18231/2394-6377.2018.0042
Abstract
Oxygen free radicals generated during radiation injury damage human erythrocyte membrane proteins including spectrin and band 3 protein. Results show an appreciable degree of spectrin and band 3 protein loss of about 55-65% due to crosslinking, and proteolysis when sodium dodecyl sulphate polyacrylamide gel electrophoresis carried out on erythrocyte ghosts. Oxidative damage to membrane proteins lead to degradation of its cytoskeletal components.
Keywords: Spectrin, Band 3 protein, Erythrocyte ghosts, Oxygen free radicals
How to cite : Audi M G, Degradation of Spectrin and band 3 protein. Int J Clin Biochem Res 2018;5(2):206-208
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