International Journal of Clinical Biochemistry and Research

Print ISSN: 2394-6369

Online ISSN: 2394-6377

CODEN : IJCBK6

International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...

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Original Article


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206-208


Authors Details

Manisha G. Audi


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Degradation of Spectrin and band 3 protein


Original Article

Author Details : Manisha G. Audi

Volume : 5, Issue : 2, Year : 2018

Article Page : 206-208

https://doi.org/10.18231/2394-6377.2018.0042



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Abstract

Oxygen free radicals generated during radiation injury damage human erythrocyte membrane proteins including spectrin and band 3 protein. Results show an appreciable degree of spectrin and band 3 protein loss of about 55-65% due to crosslinking, and proteolysis when sodium dodecyl sulphate polyacrylamide gel electrophoresis carried out on erythrocyte ghosts. Oxidative damage to membrane proteins lead to degradation of its cytoskeletal components.

Keywords: Spectrin, Band 3 protein, Erythrocyte ghosts, Oxygen free radicals


How to cite : Audi M G, Degradation of Spectrin and band 3 protein. Int J Clin Biochem Res 2018;5(2):206-208

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