International Journal of Clinical Biochemistry and Research

Print ISSN: 2394-6369

Online ISSN: 2394-6377

CODEN : IJCBK6

International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...

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Original Article


Article page

431-434


Authors Details

Balakrishnan .M, K. Sumathi, Pinky Karam, Rajarathinam


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Dendritic cells and vitamin D in dry eye disease


Original Article

Author Details : Balakrishnan .M, K. Sumathi, Pinky Karam, Rajarathinam

Volume : 5, Issue : 3, Year : 2018

Article Page : 431-434

https://doi.org/10.18231/2394-6377.2018.0091



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Abstract

To study the role of dendritic cells and vitamin D in troublesome evaporative dry eye diseases.
Materials and Methods: This is a cross sectional study which includes 108 patients having evaporative dry eye disease and 86 normal healthy volunteers. Ocular surface index, Shirmer’s test and tear film break up time, corneal dendritic cell density, vitamin D and cytokines in serum/tear were estimated. Vitamin D, cytokine in serum/tear and corneal dendritic cell density were estimated.
Result: Higher dendritic cell density noticed in evaporative dry eye disease patients compared to control group volunteers and revealed positive correlation with ocular surface index (P<0> Conclusion: Vitamin D has significant role in dry eye disease and its inflammation. Vitamin D therapy can be considered as an added treatment for dry eye disease.

Keywords: Dendritic cells, Vitamin D, Inflammatory cells, Dry eye.


How to cite : Balakrishnan .m, Sumathi K, Karam P, Rajarathinam, Dendritic cells and vitamin D in dry eye disease. Int J Clin Biochem Res 2018;5(3):431-434

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