International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 5, Issue : 4, Year : 2018
Article Page : 565-569
https://doi.org/10.18231/2394-6377.2018.0120
Abstract
Introduction: Malaria is life threatening protozoal infection caused by plasmodium species and it is major health problem in India. Electrolyte alternation is commonly occurring in infections like malaria due to effects of parasitaemia on host cells. The objectives of study were to assess serum level of sodium, potassium and chloride in malaria cases and to find association of electrolyte alteration with severity of malaria infection in different type of malaria.
Materials and Methods: Total 70 cases of P. falciparum, 70 cases of P. vivax and 70 age matched healthy controls were included in the study. Diagnosis of malaria was confirmed by QBC (Quantified buffy coat) malaria test. Estimation of electrolyte was done by direct ISE method.
Result: There were significantly decreased in mean sodium, potassium and chloride level in P. falciparum malaria cases compare to controls (P< 0> Conclusion: Hyponatraemia, hypokalaemia and hypochloremia are found in malaria particularly in P. falciparum type. Hyponatremia and hypokalemia are associated with severity of malaria infection.
Keywords: Hyponatraemia, Hypokalaemia, Hypochloremia, Malaria, Serum electrolytes.
How to cite : Dholariya S, Takodara S, Study to evaluate serum sodium, potassium and chloride level in malaria and its association with severity of malaria. Int J Clin Biochem Res 2018;5(4):565-569
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