International Journal of Clinical Biochemistry and Research

Print ISSN: 2394-6369

Online ISSN: 2394-6377

CODEN : IJCBK6

International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...

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Original Article


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583-587


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Mugdha Dilip Garule, Pravin Narayan Baravkar*, Shilpa Aditya Pratinidhi


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Comparison of LDL-cholesterol estimated by various formulae with directly measured LDL-cholesterol in a tertiary care centre of Maval Taluka

Original Article

Author Details : Mugdha Dilip Garule, Pravin Narayan Baravkar*, Shilpa Aditya Pratinidhi

Volume : 5, Issue : 4, Year : 2018

Article Page : 583-587

https://doi.org/10.18231/2394-6377.2018.0124



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Abstract

Introduction: Low-density Lipoprotein Cholesterol (LDL-C) concentration in blood gives indication of cardiovascular disease risk. LDL-C may vary at various strata of Triglycerides and in metabolic diseases like Diabetes Mellitus. Measurement of LDL-C directly on laboratory instruments is the best method but is costly. It can also be estimated using various formulae. Our study involves the comparison of LDL-C measured directly with LDL-C estimated by calculations using various formulae.
Materials and Methods: Lipid profile data was collected from Central Clinical Laboratory of MIMER Medical College and hospital, Talegaon Dabhade. Serum LDL-C values were estimated by calculation from Triglycerides (TG), Total Cholesterol (TC) and High-density lipoprotein cholesterol (HDL-C) values, using Friedewald’s, Cordova and Cordova, Vujovic, Anandaraja, Puavillai, and Hattori formula. Data of Direct LDL-C and LDL-C estimated by various formulae were compared and correlated at various levels of TG.
Result: Puavillai formula correlates the best with Direct LDL-C at TG




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