Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 5, Issue : 4, Year : 2018
Article Page : 608-612
https://doi.org/10.18231/2394-6377.2018.0129
Abstract
Introduction: Diabetic nephropathy is one of the leading complications of longstanding diabetes mellitus. With the background of inflammation, there is need for laboratory tests for early diagnosis and prevention of diabetic nephropathy.
Materials and Methods: A cross sectional study done after screening, patients satisfying the inclusion and exclusion criteria 50 patients of type II diabetic patients with nephropathy (Group I) and 50 type II diabetic patients without nephropathy(Group II) were included in the study. Serum uric acid was estimated by standard enzymatic uricase method on autoanalyser ADVIA 1800. Serum urea was estimated by urease method and serum creatinine was estimated by Jaffe’s method and Sr.Uric Acid by uricase method using fully autoanalyzer ADVIA 1800.
Results: The mean age in group I was 59 + 9.28 years and group II was 56.2 + 11.47 years. The serum Uric Acid was 9.51 +2.46 (mg/dl) in group I and statistically significant (p<0>+ 1.68 mg/dl. The Serum creatinine in group I (6.68 + 2.94 mg/dl) and statistically significant p<0>+ 0.77 mg/dl). There was positive correlation between Sr.Uric Acid and Sr. Creatinine (r=0.625, p<0 r=0.542, r=0.841,>
Conclusion: Regular detection can help the clinician to take appropriate action to delay complications which in turn may help preserve renal function in DN patients.
Keywords: Creatinine, Urea, Fasting blood glucose, Urine albumin.
How to cite : Baviskar P. A, Guha Niyogi Ni, Patil V W, Bagle T. R, Evaluation of serum uric acid in type two diabetic nephropathy patients. Int J Clin Biochem Res 2018;5(4):608-612
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