International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Null
Author Details :
Volume : 6, Issue : 1, Year : 2019
Article Page : 2-6
https://doi.org/10.18231/2394-6377.2019.0002
Abstract
Introduction: Rising prevalence of obesity represents rapidly growing threat for Indian subcontinent. Dyslipidemia in obesity accelerates the process of atherogenesis; though its occurrence can’t be underestimated in apparently normal individual lipids. This warrants need of precise measures to predict dyslipidemia beyond routine lipid parameters. Atherogenic Index of Plasma, Atherogenic Coefficient & Lipid Accumulation Product have gained attention in this regard.
Aims and Objectives: This cross sectional study aimed at assessing usefulness of calculated lipid indices over individual lipids as potential predictors of atherosclerosis in obesity.
Materials and Methods: The study enrolled 100 apparently healthy overweight & obese cases and 100 healthy controls. Fasting blood sample was collected for lipid profile parameters. Statistical analysis was done by SPSS software.
Results: The levels of TC(211.4+ 36.2/173.9+21.4), TAG (162.9+41.5/124.6+26.3), AIP (0.23+0.11/0.08+0.03), AC (4.3+1.4/2.7+1.1) & LAP (31.3+8.6/24.3+6.2) were elevated while HDL (41.7+9.2/ 52.2+8.3) levels were founder to be low in cases compared to controls (p<0>Cases having raised AIP and LAP outnumbered than those with atherogenic dyslipidemia.
Conclusion: Calculated lipid indices proved to be better than conventional lipid parameters as simple, sensitive & independent tools to screen high risk individuals for atherogenesis in obesity especially in Indian scenario with limited resources.
Keywords: Obesity, Atherogenic index of plasma, atherosclerosis, Lipid accumulation product, Atherogenic coefficient.
How to cite : Bakshi A, Bavikar J, Asegaonkar S, Comparative study of calculated lipid indices viz atherogenic index of plasma, atherogenic coefficient and lipid accumulation product over conventional lipid profile parameters as better predictors of atherosclerosis in obesity: A cross sectional study. Int J Clin Biochem Res 2019;6(1):2-6
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