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Study of Paraoxonase, Catalase, HDL-Cholesterol and Malondialdehyde Levels in NIDDM

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Author Details : Anuradha Katti-Suryawanshi, Shailaja Avinash Katti, D.S. Jayaprakash Murthy, Abdul Kayum Shaikh

Volume : 2, Issue : 3, Year : 2015

Article Page : 154-161

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Abstract

Diabetes Mellitus (DM) is an important cause of morbidity and mortality through its various complications. A decrease in Paraoxonase 1 (PON1) activity in diabetes is associated with occurrence of vascular complications. Our objectives were to estimate PON1 activity, Catalase (CAT) activity and Malondialdehyde (MDA) levels in Non-Insulin Dependent Diabetes Mellitus (NIDDM) cases and controls. We also had an objective to establish possible relationship between PON1, High Density Lipoprotein-Cholesterol (HDL- Cholesterol), CAT, MDA levels and to correlate CAT/PON1 ratio with Glycosylated Hemoglobin (HbA1c) levels.

Keywords: Diabetes Mellitus, Paraoxonase, Oxidative stress, CAT/PON1 ratio

How to cite : Katti-suryawanshi A, Katti S A, Murthy D J, Shaikh A K, Study of Paraoxonase, Catalase, HDL-Cholesterol and Malondialdehyde Levels in NIDDM. Int J Clin Biochem Res 2015;2(3):154-161

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