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A Comparative Study on Plasma Fibrinogen and hs-CRP in Metabolic Syndrome

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Author Details : Shifa K, Jithesh T.K., Parwathi K Warrior, Liji K

Volume : 2, Issue : 3, Year : 2015

Article Page : 162-165

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Abstract

Back ground &Objective: Metabolic syndrome (MS) comprises a group of various metabolic abnormalities related with high risk of cardiovascular disease. The relationship of plasma fibrinogen and hs-CRP levels with MS remains inconclusive. The aim of this study was to assess the correlation of fibrinogen and hs-CRP levels in metabolic syndrome.

Methods: It is a case control study. Detailed clinical, epidemiological and anthropometric characteristics were recorded using pro-forma. 5ml fasting venous blood collected from all the subjects after getting the informed consent.The blood samples thus obtained was used for studies including Lipid profile, hs-CRP, blood sugar and plasma fibrinogen.

Results: Fibrinogen and hs-CRP levels show significant increase in MS group. But there is no significant correlation between fibrinogen and hs-CRP levels.

Interpretation & Conclusion: Hyper fibrinogenemia and an increase in hs-CRP level in the test population explain the increased cardiovascular risk. Plasma determination of these inflammatory biomarkers might have a role in predicting the severity of metabolic syndrome.

 

Key words: Metabolic syndrome, Fibrinogen, hs-CRP

How to cite : Shifa K, T.k. J, Warrior P K, Liji K, A Comparative Study on Plasma Fibrinogen and hs-CRP in Metabolic Syndrome. Int J Clin Biochem Res 2015;2(3):162-165

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