International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 6, Issue : 2, Year : 2019
Article Page : 152-156
https://doi.org/10.18231/j.ijcbr.2019.036
Abstract
Introduction: Diabetic nephropathy has become the single most important cause of end stage renal disease worldwide. Detection of early stages of diabetic nephropathy with sensitive tests may be useful to prevent progression of nephropathy. The present study was undertaken to study the serum sialic acid levels and microalbuminuria and to assess whether there is a relationship between these two with glycemic control and other parameters in diabetic nephropathy patients.
Materials and Methods: A total number of 100 subjects participated in present study including 50 clinically diagnosed cases of type-2 diabetic nephropathy patients. Fasting and post-prandial blood sugar, urea, creatinine, serum sialic acid and urinary microalbumin levels were estimated.
Results: The mean fasting blood sugar values in cases (181.40±45.82) as compared to controls (89.62±12.53) is statistically significant (p<0 xss=removed xss=removed xss=removed xss=removed>
Conclusion: Estimation of serum sialic acid prior to microalbumin in diabetic patients is helpful in assessing the glycemic control and identify the risk of nephropathy which is the main cause for mortality and morbidity among type-2 diabetes mellitus patients.
Keywords: Serum sialic acid, Microalbumin, HbA1c, Nephropathy, Type-2 diabetes mellitus.
How to cite : Kumar B S, Khan S A, Baba K S S, Satyanarayana P V, Mohan I K, Sialic acid: an early sensitive marker improves detection of nephropathy in type-2 diabetes mellitus patients. Int J Clin Biochem Res 2019;6(2):152-156
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