International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 6, Issue : 2, Year : 2019
Article Page : 209-212
https://doi.org/10.18231/j.ijcbr.2019.046
Abstract
Introduction: Pre-eclampsia (PE) a pregnancy specific disease, the most common cause of fetal and maternal death yet, no specific prevention and treatment is available. Reliable biochemical markers for prediction and diagnosis of PE can have a better impact on maternal health and several of these markers have been suggested till now. Recently Ischemia Modified Albumin (IMA) has emerged as a marker in different diseases, where ischemia is the origin or consequence behind disease pathology.
Materials and Methods: 30 patients with PE were selected for the study and compared with 30 pregnant healthy controls. IMA IMA/albumin with other routine biochemical markers was estimated in these patients.
The results were then statistically analysed.
Results: IMA levels were found significantly raised in PE patients as compared to normal pregnant controls (p value<0 r=+0.3>
Conclusion: IMA generated by hypoxia/ischemia driven oxidative stress is also raised in PE, hence can be used as a biomarker in PE. Further studies are needed to establish the relationship between IMA, disease process and its association with severity of the disease.
Keywords: Pre-eclampsia, Ischemia Modified albumin.
How to cite : Roy N, Sahana S, Serum ischemia modified albumin as a potent biochemical marker in pre-eclampsia patients attending a tertiary care hospital in central India. Int J Clin Biochem Res 2019;6(2):209-212
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