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Comparative study of serum lipid profile level between chronic kidney disorder patients and healthy controls

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Original Article

Author Details : Ketan Mangukiya, Sarita H Patel*, Milav Bhavsar, Alok Parekh, Rinku Bhanavadiya

Volume : 6, Issue : 3, Year : 2019

Article Page : 375-379

https://doi.org/10.18231/j.ijcbr.2019.081

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Abstract

Introduction: Several factors contribute to atherogenesis and cardiovascular disease in patients with CKD.
Notable among the CKD-induced risk factors are lipid disorders, oxidative stress, inflammation, physical
inactivity, anemia, hypertension, vascular calcification, endothelial dysfunction, and depressed nitric oxide
availability.
Objective: The objective is to Measure lipid profile in a patients of chronic kidney disorder (CKD) and
compare their level with healty control.
Materials and Methods: Study includes total 100 particpants. Among them 50 patients of CKD of age
group between 20 to 70 year and 50 healthy controls. Fasting blood samples were collected from both
groups and measurement of the lipid profile, FBS, PPBS, serum creatinine and blood urea was done.
Results: There is increased level of serum cholesterol and triglyceride was found in CKD patients as
compared to control group but when we compared it with control group by calculating p value the difference
of significance was found only in case of cholesterol level. Serum LDL was also significantly raised in
patients of CKD compared to controls.
Conclusion: There is significant amount of dyslipidemia is found in patients of CKD. So treatment of
dyslipidemia will reduce mortality in CKD patients.

Keywords: CKD, lipid Profile, Hypertension, Diabetes mellitus.

How to cite : Mangukiya K, Patel S H, Bhavsar M , Parekh A, Bhanavadiya R, Comparative study of serum lipid profile level between chronic kidney disorder patients and healthy controls. Int J Clin Biochem Res 2019;6(3):375-379

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