ANTI INFLAMMATORY ROLE OF SCENT LEAF (OCIMUM GRATISSIMUM L.) AND BITTER LEAF (VERNONIA AMYGDALINA D.) ON SIMULATED GASTROINTESTINAL DIGESTION

Authors: Esther Udo Umoh, Bridget Kpomah, Godspower Oyubu, Daramola Festus Olayinka, Asimi Tawakalitu Temitope, Julius John Dimas

DOI: 10.18231/j.ijcbr.11445.1760587515

Keywords: Inflammatory, Sent Leaf, Bitter leaf, anti-inflammatory drugs, medicine plant

Background/ Introduction: Inflammatory is a part of the body’s immune response to any kind of injury. Some of the sings of inflammation are pain, redness heat and swellings. It could be acute or chron...

"AAggravated dyslipidemia in Comorbid T2DM and Hypothyroidism: A Comparative Analysis” among the peoples of North Bihar

Authors: Zeenat Inam, Raman Kumar Rana, Ezaz Zafar

DOI: 10.18231/j.ijcbr.12165.1852744896

Keywords: Keywords: Dyslipidemia, Type 2 Diabetes Mellitus, Hypothyroidism, Lipid Profile, Comorbidity, Cardiovascular Risk

Background: Type 2 diabetes mellitus (T2DM) and hypothyroidism are prevalent endocrine disorders, each associated with significant metabolic disturbances. Their coexistence may exacerbate glycemic and...

Serum Pentosidine – A Surrogate Marker of Vascular Complications in Type 2 Diabetes Mellitus

Authors: SABIHA NAZ, TRIPTI SAXENA, PAWAN KUMAR KARE, SIMMI DUBE

DOI: 10.18231/j.ijcbr.12870.1971565007

Keywords: Key words: Pentosidine, vascular complications, surrogate marker.

Introduction: As a result of prolonged hyperglycemia in diabetic patients, glucose reacts with proteins non-enzymatically to produce Advanced Glycation End products (AGES) such as Pentosidine (PEN). T...

Association of GATA4 polymorphisms with the risk of hypospadias and congenital heart defects in Indian children: A Review

Authors: DIVIA PAUL ARICATT, NEHA SAMAPRIYA, SOMESH M.S.

DOI: 10.18231/j.ijcbr.13060.1759558940

Keywords: GATA4 polymorphism, Congenital heart disease, Hypospadias, Developmental anomalies, South Asian population

Background: Congenital heart disease (CHD) and hypospadias are common developmental anomalies with both affecting approximately 1% of neonates. Emerging data suggest these conditions often co-occur, h...

Should Arterial Blood-Gas Analysis be done in all ICU patients?

Authors: Asha Khubchandani, Drishya Pradeep Nair

DOI: 10.18231/j.ijcbr.13524.1760157016

Keywords: Arterial Blood-Gas Analysis,ABG, ICU, Critical care

Introduction: Understanding and use of blood gas analysis enable providers to interpret respiratory, circulatory and metabolic disorders and its severity. It is an important tool of analysis especiall...

Validation and Performance Evaluation of Biochemical Assays in Pleural Fluid, Ascitic Fluid, and Cerebrospinal Fluid: A Comprehensive Precision, Sensitivity, Accuracy, and Linearity Study

Authors: Jayesh Prabhakar Warade, Ashish Anjankar

DOI: 10.18231/j.ijcbr.13447.1759901703

Keywords: Body fluids, Validation, Diagnostics,sensitivity, accuracy, linearity

Background: The validation of biochemical assays in pleural fluid, ascitic fluid, and CSF is essential for accurate diagnosis, disease monitoring, and treatment evaluation. This study aims to assess t...