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A study of pre-analytical variables and quality improvement in testing process of clinical laboratory
- Author Details:
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Mahantesh Patil
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Meera S
Introduction: Laboratory tests are important to diagnose the diseases, to monitor the progress and to see the response to the treatment of patients. Pre-analytical variables include specimen collection, timing, transportation & handling of the sample processing.
Methodology: The data were obtained from Biochemistry Central Laboratory, Descriptive Cross Sectional study design was used and data were entered in excel and analysed by using Epi-info Software version 3.4.3. Descriptive statistics like frequencies and percentages were calculated.
Results: The total number of samples received by the laboratory for a period of two months was 7333 and analyzed for pre-analytical errors in those samples. The most common pre-analytical error was wrong ordering which is 16.73% & followed by hemolysed sample, insufficient quantity, mixed with saline, empty tubes and the least one was mismatched samples.
Conclusion: Quality improvement in the pre-analytical phase helps laboratories to deliver more timely and accurate test results for clinicians.
Keywords: Pre-analytical errors, Turnaround time, Total testing process
References
- Medical laboratories. Particular requirements for quality and competence ISO 15189:2007.
- The European Health Committee. Committee of experts on management of safety and quality in healthcare [Prevention of adverse effects in healthcare: a system approach] Strasbourg: 2004. Council of Europe CDSP (2004) 41. (In Spanish)
- Kalra J. Medical errors: impact on clinical laboratories and other critical areas. Clinical biochemistry. 2004 Dec 31;37(12):1052-62.
- Carl A, Burtis, Edward R Ashwod, David E Bruns. Tietz text book of clinical biochemistry and molecular diagnostics.4 th ed. Elsevier: 2006;449.
- Nichols JH. Laboratory quality control based on risk management. Ann Saudi Med. 2011;31:223–8.
- Malone B. A new approach to quality control-How can risk management help labs? Clinical Laboratory News. 2011;37:11.
- Boone DJ. How can we make laboratory testing safer? Clin Chem Lab Med. 2007;45:708–11.
- Plebani M, Ceriotti F, Messeri G, Ottomano C, Pansini N, Bonini P. Laboratory network of excellence: Enhancing patient safety and service effectiveness. Clin Chem Lab Med. 2006;44:150–60.
- Plebani M, Carraro P. Mistakes in a stat laboratory: types and frequency. Clin Chem. 1997;43:1348–51.
- Wiwanitkit V. Types and frequency of preanalytical mistakes in the first Thai ISO 9002:1994 certified clinical laboratory, a 6 month monitoring. BMC Clin Pathol. 2001;1:5.
- Wagar EA, Tamashiro L, Yasin B, Hilborne L, Bruckner DA. Patient safety in the clinical laboratory. A longitudinal analysis of specimen identification errors. Arch Pathol Lab Med. 2006;130:1662–8.
- Llopis MA, Trujillo G, Llovet MI, Tarrés E, Ibarz M, Biosca C, et al. Quality indicators and specifications for key analytical-extranalytical processes in the clinical laboratory. Five years’ experience using the Six Sigma concept. Clin Chem Lab Med. 2011;49:463–70.
- Beletic A, Sumarac Z, Milinkovic N, Ignjatovic S, Majkic-Singh N. Experience in introduction of quality indicators in pre-analytical phase. 2nd EFLM-BD European Conference on Preanalytical Phase. Biochem Med. 2013;23:A46.
- Bonini P, PlebaniM, Ceriotti F, et al. Errors in laboratory medicine. Clin Chem. 2002;48:691-698.
- Carraro P, Servidio G, Plebani M. Hemolyzed Specimens: A Reason for Rejection or a Clinical Challenge? [Letter] Clin Chem. 2000;46:306–7.
- NCCLS – Procedures for the Collection of Diagnostic Blood Specimens by Venipuncture; Approved Standard, Fifth Edition, December 2003; H3-A5 Vol. 23 No. 32.
- NCCLS – Tubes and Additives for Blood Specimen Collection; Approved Standard-Fifth Edition, December 2003; H1- A5 Vol. 23 No. 33.
How to Cite This Article
Vancouver
Patil M, S M. A study of pre-analytical variables and quality improvement in testing process of clinical laboratory [Internet]. Int J Clin Biochem Res. 2016 [cited 2025 Oct 28];3(3):277-279. Available from: https://doi.org/
APA
Patil, M., S, M. (2016). A study of pre-analytical variables and quality improvement in testing process of clinical laboratory. Int J Clin Biochem Res, 3(3), 277-279. https://doi.org/
MLA
Patil, Mahantesh, S, Meera. "A study of pre-analytical variables and quality improvement in testing process of clinical laboratory." Int J Clin Biochem Res, vol. 3, no. 3, 2016, pp. 277-279. https://doi.org/
Chicago
Patil, M., S, M.. "A study of pre-analytical variables and quality improvement in testing process of clinical laboratory." Int J Clin Biochem Res 3, no. 3 (2016): 277-279. https://doi.org/