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Comparison of glucose levels using glucometer and GOD-POD Method in diabetic patients
- Author Details:
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Sherie Pankaj Sharma
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Ashish Prakash Anjankar
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Anita Kale
Introduction: Glucometer is widely used at hospitals and homes as a first line tool to get an idea about the current blood glucose levels. Since glucometers are used for making important decisions, it is essential that their accuracy should be comparable to those of standard laboratory analyzers. So the present study was aimed to compare and correlate the glucose levels using glucometer and GOD-POD method in diabetic patients.
Methods: 60 diagnosed type 2 diabetes mellitus patients were selected for the study after institutional ethical committee’s clearance was obtained. These were divided into three groups based on their plasma glucose levels by GOD-POD method.
Group 1: 20 Patients having plasma glucose levels ? 110 mg/dl.
Group 2: 20 Patients having plasma glucose levels between 111 mg/dl to 250 mg/dl.
Group 3: 20 Patients having plasma glucose levels ? 251 mg/dl.
In this study, we measured plasma glucose levels of each patient simultaneously with glucometer and GOD-POD method (semi-automatic analyzer) in the clinical laboratory.
Results: In our study, we found that that at very high glucose readings (i.e. in group 3 patients having plasma glucose levels ? 251 mg/dl), glucometer overestimates glucose results. So, these values do not accurately reflect actual plasma glucose levels.
Conclusions: Very high glucose values obtained using glucometers should be cautiously interpreted and verified with centralized laboratory. The current practice of performing only single readings with glucometers can lead to misdiagnosis. Medical professionals should depict diabetic patients the importance of periodic centralized laboratory glucose testing.
Keywords: Diabetes, Glucose levels, Glucometer, GOD-POD method
References
- Burtis CA, Ashwood ER, Bruns DE, editors. Tietz textbook of clinical chemistry and molecular diagnostics. 4th ed. St Louis Missouri USA: Elsevier Saunders; 2006.
- Trinder P. Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann.Clin.Biochem 1969;6:24-7.
- Ellis Jacob. Point of care (near-patient) testing. Kaplan LA, Pesce AJ, Kazmierezak SC. Clinical Chemistry 3 rd Ed: New York: Mosby; 1996.p.313-22.
- Sacks DB, Bruns DE, Goldstein DE, Maclaren NK, McDonald JM, Parrott M. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem 2002;48(3):436-72.
- Louie RF, Tang Z, Sutton DV, Lee JH, Kost GJ. Point-of- care glucose testing: effects of critical care variables, influence of reference instruments, and a modular glucose meter design. Arch Pathol Lab Med. 2000;124:257–266.
- Winkelman JW, Wybenga DR, Tanasijevic MJ. The fiscal consequences of central vs distributed testing of glucose. Clin Chem. 1994;40:1628–1630.
- Koschinsky T, Jungheim K, Heinemann L. Glucose sensors and the alternate site testing–like phenomenon: relationship between rapid blood glucose changes and glucose sensor signals. Diabetes Technol Ther. 2003;5:829–842.
- Tonyushkina K, Nichols JH. Glucose Meters: A review of technical challenges to obtaining accurate results. J Diabetes Sci Technol. 2009; 3:971–80.
- D’Orazio P, Burnett RW, Fogh-Andersen N, Jacobs E, Kuwa K, K_lpmann WR, Larsson L, et al. Approved IFCC recommendation on reporting results for blood glucose. Clin Chem. 2005;51:1573-6.
- Geneva: International Organization for Standardization;
- International Organization for Standardization. Determination of performance criteria for in vitro blood glucose monitoring systems for management of human diabetes mellitus. ISO 15197.
- American Diabetes Association. Self-monitoring of blood glucose. Diabetes Care. 1994;17:81–6. [PubMed]
- Reeves ML, Forhan SE, Skyler JS, and Peterson CM. Comparison of Methods for Blood Glucose Monitoring. DIABETES CARE 30:404-406, MAY-JUNE 1981.
- Khan AI, Vasquez Y, Gray J, Wians F, and Kroll M. The variability of results between point-of-care testing glucose meters and the central laboratory analyzer. Archives of Pathology Laboratory Medicine, 2006;130(10):1527-1532.
- Baig, A., Siddiqui, I., Jabbar, A., Azam, S. I., Sabir, S., Alam, S., et al. (2007).Comparison between bed side testing of blood glucose by glucometer vs. centralized testing in a tertiary care hospital. J Ayub Med Coll Abbottabad. 2007;19(1):25-29.
- Clarke WL, Cox D, Gonder-Frederick LA, et al. Evaluating clinical accuracy of systems for self- monitoring of blood glucose. Diabetes Care. 1987;10:622–628.
- Chen E, Nichols J, Duh S, Hortin G: Performance evaluation of blood glucose monitoring devices. Diabetes Technol Ther 2003;5:749–768.
- Tang Z, Lee JH, Louie RF, Kost GJ. Effects of different hematocrit levels on glucose measurements with handheld meters for point-of-care testing. Arch Pathol Lab Med. 2000;124:1135-40.
- Louie RF, Tang Z, Sutton DV, Lee JH, Kost GJ. Pointof- care glucose testing: effects of critical care variables influence of reference instruments, and a modular glucose meter design. Arch Pathol Lab Med. 2000;124:257-66.
- 19.Tang Z, Louie R, Payes M, Chang K, Kost G: Oxygen effects on glucose measurements with a reference analyzer and three handheld meters. Diabetes Technol Ther 2000;2:349–362.
- Tang Z, Louie R, Lee J, Lee D, Miller E, Kost G: Oxygen effects on glucose meter measurements with glucose dehydrogenase- and oxidase-based test strips for point-of- care testing. Crit Care Med 2001;29:1062–1070.
- Dungan K, Chapman J, Braithwaite SS, Buse J. Glucose measurement: confounding issues in setting targets for inpatient management. Diabetes Care. 2007;30(2):403–9. Sherie Pankaj Sharma et al. Comparison of glucose levels using glucometer and GOD-POD Method…. International Journal of Clinical Biochemistry and Research 2017;4(1):6-10 10
- Tang Z, Du X, Louie RF, Kost GJ. Effects of pH on glucose measurements with handheld glucose meters and a portable glucose analyzer for point-of-care testing. Arch Pathol Lab Med. 2000;124:577–582.
- Bergenstal RM. Evaluating the accuracy of modern glucose meters. Insulin. 2008;3(1):5–14. 24. Johnson R, Baker J: Error detection and measurement in glucose monitors. Clini Chim Acta 307:61–67,2001.
- Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307-10.
How to Cite This Article
Vancouver
Sharma SP, Anjankar AP, Kale A. Comparison of glucose levels using glucometer and GOD-POD Method in diabetic patients [Internet]. Int J Clin Biochem Res. 2017 [cited 2025 Oct 28];4(1):6-10. Available from: https://doi.org/
APA
Sharma, S. P., Anjankar, A. P., Kale, A. (2017). Comparison of glucose levels using glucometer and GOD-POD Method in diabetic patients. Int J Clin Biochem Res, 4(1), 6-10. https://doi.org/
MLA
Sharma, Sherie Pankaj, Anjankar, Ashish Prakash, Kale, Anita. "Comparison of glucose levels using glucometer and GOD-POD Method in diabetic patients." Int J Clin Biochem Res, vol. 4, no. 1, 2017, pp. 6-10. https://doi.org/
Chicago
Sharma, S. P., Anjankar, A. P., Kale, A.. "Comparison of glucose levels using glucometer and GOD-POD Method in diabetic patients." Int J Clin Biochem Res 4, no. 1 (2017): 6-10. https://doi.org/