Biochemical role of serum uric acid and cardiac enzymes in acute myocardial infarction

• Author Details:   
• S J. Basha ^*
• M Anil Kumar
• K K.L. Prasad

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Introduction: Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality worldwide. In India cardio vascular disease is the leading cause of death.
Materials and Methods: It is a comparative study was conducted among 50 cases of acute MI were taken in the study group, 100 age and gender matched individuals served as control group. Serum uric acid levels were estimated on the day of admission during the hospital stay. Additional parameters like CPK, CKMB, SGOT, and LDH were also estimated.
Results: Serum uric acid levels (mg/dl) is significantly increased in cases as compared to healthy controls [5.069 ± 1.244 versus 3.73 ± 0.388; (P value < 0> Conclusion: The present study showed that the serum uric acid levels are higher in patients of acute myocardial infarction as compared to normal healthy individuals thus serum uric acid plays an important role in the early diagnosis of acute myocardial infarction. Markers like CK-MB, CPK, SGOT and LDH also play in important in early diagnosis of acute myocardial infarction.

Keywords: Acute myocardial infarction, Biochemical role, Cardiac enzymes, Serum uric acid, MIMS.