International Journal of Clinical Biochemistry and Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-6369
Online ISSN: 2394-6377
CODEN : IJCBK6
International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 11, Issue : 4, Year : 2024
Article Page : 254-259
https://doi.org/10.18231/j.ijcbr.2024.038
Abstract
Context: Chronic kidney disease is a worldwide disease with an estimated prevalence of 10% in 2020. In Côte d'Ivoire, the prevalence of this disease is not well known, but hospital studies show prevalences of 7 to 46%. In 2020, hemodialysis patients are particularly at risk of contracting COVID-19. Studies have shown that vitamin D supplementation can not only reduce the risk of getting acute respiratory infections, but has also been associated with a lower susceptibility to severe COVID-19. To this end, a study was undertaken to assess the impact of the pandemic on hemodialysis patients in the public sector of Abidjan, according to their vitamin D status.
Materials and Methods: In a cross-sectional study conducted from November 2021 to August 2022, we included 280 patients with end-stage CKD treated with hemodialysis at the CNPTIR in Abidjan. The collection of epidemiological and clinical data was done on the basis of a questionnaire on the one hand and the medical records of the patients on the other. Vitamin D concentration and COVID-19 serology were determined by the ELFA method with immunochemical detection.
Results : The mean age of the patients was 45.90 ± 12.76 and 66.85% of them were men. 42.70% of patients had been dialysis for more than 5 years. 3/4 of the study population had a positive serology for COVID-19. The mean vitamin D concentration in patients was 23.04 ng/ml of which 38.20% were vitamin D deficient. 94.57% of patients did not experience severe signs of COVID-19. There was no significant difference between mean vitamin D concentrations in serology-positive versus serology-negative patients, and mean vitamin D values in patients with severe and non-severe symptomatology.
Conclusion: Our study did not show a protective effect of vitamin D against covid-19 in Ivorian hemodialysis patients.
Keywords: COVID19, Vitamin D, hemodialysis, West African
How to cite : Yayo S E, Mireille Y E Y C, Kouacou K M, Nanihio M, Hauouhot A M, Research on a protective effect of Vitamin D in the context of COVID-19 in adults on West African hemodialysis. Int J Clin Biochem Res 2024;11(4):254-259
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