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Association of hypothyroidism and polycystic ovary syndrome (PCOS)

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Original Article

Author Details : K Lavanya, Santhi Silambanan*, M Ganesh

Volume : 6, Issue : 3, Year : 2019

Article Page : 405-409

https://doi.org/10.18231/j.ijcbr.2019.087

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Abstract

Introduction: Polycystic ovarian syndrome (PCOS) and hypothyroidism are the most common endocrine
disorders in women of reproductive age group and both these disorders present with complaints of
menstrual irregularities like oligomenorrhoea, secondary amenorrhoea and sometimes menorrhagia. The
relationship between hypothyroidism and PCOS is not clearly understood.
Aim and Objective: To determine the association between thyroid profile and polycystic ovary syndrome
(PCOS)
Materials and Methods: This is a retrospective study on 71 patients with PCOS at Sri Ramachandra
medical centre, over a period of 6 months. In this study, PCOS was diagnosed based on Rotterdam criteria
and patient details regarding history, physical examination and thyroid profile were obtained. In all these
patients, thyroid profile was analysed in Beckman coulter DXI 800 based on the principle CLIA.
Results: Statistical analysis was done using SPSS software version 13.0. Student t test was performed and
p value < 0> hypothyroidism and other presenting complaints.
Discussion: PCOS was more common in the age group of 26-30 years. 18% of PCOS patients diagnosed to
have hypothyroidism, 4% patients found to have Sub-clinical hypothyroidism and rest 78% were euthyroid.
46% of PCOS patients presented with complaints of irregular menstrual cycle, 31% with complaints of
infertility and 23% with other complaints.
Conclusion: There is increased prevalence of hypothyroidism in patients with PCOS. Similarly, the
coexistence of hypothyroidism and PCOS can lead to severity of complaints in hypothyroid patients.
Screening for hypothyroidism in PCOS patients will decrease the morbidity. Thus improving quality of
life.

Keywords: Hypothyroidism, Infertility, PCOS, Rotterdam criteria, Subclinical hypothyroidism, TSH.

How to cite : Lavanya K, Silambanan S, Ganesh M, Association of hypothyroidism and polycystic ovary syndrome (PCOS). Int J Clin Biochem Res 2019;6(3):405-409

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